M
| Name | Life | Profession | Cause of death | Reference |
|---|---|---|---|---|
| Billy Mackenzie | 1957–1997 | Musician (the Associates) | Overdose of amitriptyline, paracetamol and other prescription drugs. Suicide. | |
| Chris Mainwaring | 1965–2007 | Australian football player | Cocaine overdose. Accidental. | |
| Bibek Maitra | 19??–2006 | Politician | Unspecified drug overdose. | |
| Jesse Mahelona | 1983–2009 | American football player | Motor-vehicle collision. Malehona was under the influence of alcohol. | |
| Vickie Lynn Marshall, aka Anna Nicole Smith | 1967–2007 | Playboy playmate, actress | Lethal combination of chloral hydrate and various benzodiazepines. | |
| Adrienne Nicole Martin | 1983–2010 | Model, girlfriend of August Busch IV | Oxycodone overdose. Accidental. | |
| Andrew Martin, aka Test | 1975–2009 | Professional wrestler | Oxycodone overdose. Accidental. | |
| Thalia Massie | 1911–1963 | Wife | Barbiturate overdose. | |
| Lisa Matsumoto | 1964–2007 | Children's author | Motor-vehicle collision. Matsumoto's blood alcohol level was .242, more than 3 times the legal limit. | |
| Billy Mays | 1958–2009 | Salesperson | Heart disease with cocaine use being a "contributory cause". | |
| Joseph McCarthy | 1908–1957 | Senator | Hepatitis exacerbated by alcoholism. |
|
| Jimmy McCulloch | 1953–1979 | Musician (Wings) | Heroin overdose. | |
| Marie McDonald | 1923–1965 | Actress | Unspecified drug overdose. | |
| Robbie McIntosh | 1950–1974 | Musician (Average White Band) | Heroin overdose. | |
| Stephen McKeag | 1970–2000 | Ulster Defence Association member | Cocaine and pain killer overdose. | |
| Marguerite McNamara | 1928–1978 | Actress | Sleeping pill overdose. Suicide. | |
| Lance McNaught a.k.a Lance Cade | 1981-2010 | Professional Wrestler | Intoxication from mixed drugs complicated a cardiomyopathy. Accidental. | |
| Aimee Semple McPherson | 1890–1944 | Evangelist | Shock and respiratory failure due to overdose of prescription barbiturates. | |
| Jonathan Melvoin | 1961–1996 | Keyboardist | Heroin overdose. | |
| Mary Millington | 1945–1979 | Model, pornographic actress | Paracetamol overdose. Suicide. | |
| Keith Moon | 1946–1978 | Musician (the Who) | Overdose on anti-seizure medication prescribed for alcoholism. Accidental. | |
| Odas Moon | 1892–1937 | Pilot | Reportedly "drank himself to death". | |
| Kenneth Moore a.k.a. Big Moe | 1974–2004 | Rapper | Heart attack with Purple Drank as a contributing factor | |
| Chester Morris | 1901–1970 | Actor | Barbiturate overdose. | |
| Jim Morrison | 1943–1971 | Musician (The Doors) | Official cause of death is recorded as heart failure, though Sam Bernett claims that Morrison died in Bernett's club, with heroin overdose as the suspected cause. | |
| Norma Mortenson, aka Marilyn Monroe | 1926–1962 | Actress | Barbiturate overdose. Officially listed as "probable suicide" though several conspiracy theories exist. | |
| Louis Mucciolo, Jr., aka Louie Spicolli | 1971–1998 | Professional wrestler | Conflicting sources indicate drug overdose while some indicate coronary disease that might have been impacted by drug use. | |
| Billy Murcia | 1951–1972 | Musician (New York Dolls) | Contradicting sources report the death as alcohol related, or drowning after a drug overdose or as a drug overdose. | |
| Brittany Murphy | 1977–2009 | Actress | "ombination of pneumonia, an iron deficiency and 'multiple drug intoxication.'" | |
| Brent Mydland | 1952–1990 | Musician (the Grateful Dead) | Cocaine and morphine overdose. |
Read more about this topic: List Of Drug-related Deaths