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| Name | Life | Profession | Cause of death | Reference |
|---|---|---|---|---|
| Herb Abrams | 1954–1996 | Professional wrestling promoter | Cocaine related heart attack. | |
| Janet Achurch | 1864–1916 | Actress | Morphine overdose. | |
| Brian Adams | 1963–2007 | Professional wrestler | Painkiller overdose. Accidental. | |
| Nick Adams | 1931–1968 | Actor | Barbiturate overdose. Death officially certified as "accidental-suicidal and undetermined". High levels of sedatives were found in his blood. | |
| Stuart Adamson | 1958–2001 | Musician (Big Country) | Hanged himself under the influence of alcohol. | |
| Michael Adkisson, aka Mike Von Erich | 1964–1987 | Professional wrestler | Tranquilizer overdose. Suicide. | |
| George V | 1865–1936 | King | Cocaine and morphine overdose. Euthanasia. | |
| Asa A. Allen | 1911–1970 | Evangelist | Liver failure due to acute alcoholism. | |
| Dennis Allen | 1951–1987 | Drug dealer | Heart failure. "Pieces of his heart actually broke off after decades of heavy drug abuse". | |
| Ryūnosuke Akutagawa | 1892–1927 | Writer | Veronal overdose. Suicide. | |
| William Barnsley Allen | 1892–1933 | Army officer | Unspecified narcotic overdose. Accidental. | |
| Pier Angeli | 1932–1971 | Actress | Died of anaphylactic shock after being given a tranquilizer by her doctor. | |
| Matthew Ansara | 1965–2001 | Actor | Heroin overdose. Accidental. | |
| Chris Antley | 1966–2000 | Jockey | Severe blunt trauma. The coroner's report concluded that Antley had died of a multiple drug overdose and the injuries were likely related to a fall caused by the drugs. | |
| Jean Améry | 1912–1978 | Writer | Sleeping pill overdose. Suicide. | |
| Diane Arbus | 1923–1971 | Photographer | Consumed a number of barbiturates and then slit her wrists. Suicide. | |
| West Arkeen | 1960–1997 | Musician | Opiate overdose. Accidental | |
| Howard Arkley | 1951–1999 | Painter | Heroin overdose. Accidental. | |
| Kevyn Aucoin | 1962–2002 | Photographer, make-up artist | Kidney and liver failure due to Tylenol toxicity, as a result of a prescription painkiller addiction. |
Read more about this topic: List Of Drug-related Deaths