List of Clinical Research Topics - General Topics

General Topics

  • Clinical significance – a conclusion that an intervention has an effect that is of practical meaning to patients
  • Drug discovery – the identification of candidates, synthesis, characterization, screening, and assays for therapeutic efficacy
  • Drug development – the process of taking a new chemical through the stages necessary to allow testing in clinical trials
  • Biotechnology – the technological application that uses biological systems, living organisms to make or modify products or processes for specific use
    • Biopharmaceutical – a drug produced using biotechnology
  • Clinical trial – an experiment with human subjects to assess safety and efficacy of drugs
    • Academic clinical trials – clinical trials run at academic centers (e.g., medical schools, academic hospitals, and universities)
    • Clinical trials unit – biomedical research units dedicated to conducting clinical trials
  • Epidemiology – the study of factors affecting the health and illness of populations
    • Epidemiological methods – statistical techniques used in epidemiology
  • Evidence-based medicine – the assessment of the quality of evidence relevant to the risks and benefits of medical treatments
  • Pharmacology – the study of the interactions that occur between a living organism and drugs that alter normal biochemical function
    • Biopharmacology – the pharmacology of biopharmaceuticals
    • Clinical pharmacology – the scientific discipline focused on rational drug development and utilization in therapeutics
    • Pharmacokinetics – the study of the fate of drugs administered to the body
      • Bioequivalence – the biological equivalence of two preparations of a drug
    • Pharmacodynamics – the study of the biochemical and physiological effects of drugs on the body
    • Pharmacometrics – the science of interpreting and describing pharmacology in a quantitative fashion
  • Pharmacovigilance – the detection, assessment, understanding and prevention of adverse effects of medicines

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