Regulation
The ion channel is regulated by a ligand and is usually very selective to one or more ions like Na+, K+, Ca2+, or Cl-. Such receptors located at synapses convert the chemical signal of presynaptically released neurotransmitter directly and very quickly into a postsynaptic electrical signal.
Many LGICs are additionally modulated by allosteric ligands, by channel blockers, ions, or the membrane potential.
Read more about this topic: Ligand-gated Ion Channels
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