Levomefolic Acid - Brands

Brands

Oral doses of levomefolic acid as its calcium salt, levomefolate calcium, have been developed in Germany and are marketed under the brand name Metafolin by Merck.

  • Cerefolin NAC (5.6 mg) – Nutritional requirements of individuals under a physician's treatment for neurovascular oxidative stress or hyperhomocysteinemia, with particular emphasis for those individuals diagnosed with or at risk for mild to moderate cognitive impairment, vascular dementia, Alzheimer's disease or recurrent or ischemic.
  • Deplin (7.5 mg or 15 mg) – Dietary management of suboptimal l-methylfolate levels in patients with major depressive disorder.
  • Metanx (2.8 mg) – Dietary management of endothelial dysfunction in patients with diabetic peripheral neuropathy.
  • Néevo and NeevoDHA (1 mg) – Dietary management of those women under a physician's treatment for vitamin deficiency throughout pregnancy, postnatal and the lactating periods. Néevo is specifically indicated for: patients with high risk pregnancies, older OB patients, and patients unable to fully metabolize folic acid.
  • Zervalx (1 mg) – Dietary management of the following patient conditions: preconception hyperhomocysteinemia; intermediate to higher-risk pregnancies that require an increased dietary folate intake; hemolytic, megaloblastic or sickle cell anemia complicated by folate deficiency; and methotrexate induced plasma hyperhomocysteinemia.

The Italian company Gnosis SpA markets 3 levomefolic acid products.

  • Extrafolate (Calcium-5-MTHF (racemic mixture))
  • Extrafolate-S (levomefolate calcium)
  • Quatrefolic (glucosamine salt of 5-MTHF)

Supplement company Neurobiologix markets 2 levomefolic acid products:

  • Neuro-Immune Stabilizer Topical Cream (5-MTHF, Hydroxycobalamin, Methylcobalamin, P5P and Vitamin D)
  • Methyl Folate Plus (Calcium-5-MTHF (5 mg), folinic acid (2 mg), and niacinamide (125 mg))


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