Expression
LIF is normally expressed in the trophectoderm of the developing embryo, with its receptor LIFR expressed throughout the inner cell mass. As embryonic stem cells are derived from the inner cell mass at the blastocyst stage, removing them from the inner cell mass also removes their source of LIF.
Read more about this topic: Leukemia Inhibitory Factor
Famous quotes containing the word expression:
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Dutch expression meaning “a boor”: from the old belief that bear cubs are licked into shape by their mothers.
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