Least squares inference in phylogeny generates a phylogenetic tree based on an observed matrix of pairwise genetic distances and optionally a weight matrix. The goal is to find a tree which satisfies the distance constraints as best as possible.
Read more about Least Squares Inference In Phylogeny: Ordinary and Weighted Least Squares, Generalized Least Squares, Computational Complexity
Famous quotes containing the words squares and/or inference:
“An afternoon of nurses and rumours;
The provinces of his body revolted,
The squares of his mind were empty,
Silence invaded the suburbs,”
—W.H. (Wystan Hugh)
“Rules and particular inferences alike are justified by being brought into agreement with each other. A rule is amended if it yields an inference we are unwilling to accept; an inference is rejected if it violates a rule we are unwilling to amend. The process of justification is the delicate one of making mutual adjustments between rules and accepted inferences; and in the agreement achieved lies the only justification needed for either.”
—Nelson Goodman (b. 1906)