Kyra may refer to:
- Kyra, Cyprus, a village in Cyprus
- Kyra, Russia, a rural locality (a selo) in Kyrinsky District of Zabaykalsky Krai, Russia
- Kyra River, a river in Russia and Mongolia
- Kyra, a former snout moth genus of the Phycitini, now synonymized with Eurhodope
- Kyra Davis, an American mystery novelist
- Kyra Sedgwick, American actress