Kishi may refer to:
- Kishi (demon), a type of demon of Angola, which has two faces - one human, the other hyena
- Kishi (Bible), biblical figure
- Solofa Fatu (born 1966), professional wrestler
- an alternative spelling of Kisi, Nigeria, a town in Oyo State
Kishi is also a Japanese surname; people with this name include:
- Kishi Nobusuke (1896–1987), 56th and 57th Prime Minister of Japan
- Kishi Keiko (born 1932), actress
- Asako Kishi (born 1923), culinary critic
- Kichimatsu Kishi (died 1956), founder of an agricultural colony and a small oil company
- Matsuo Kishi (1906-1985), film critic and screenwriter
- Yoshito Kishi, Japanese-American chemist