Fictional Characters
- Khan, one of the villains in the Broken Sword: The Shadow of the Templars computer game
- Khan, a Chinese-American detective from the Khan! 1975 US television series
- Khan (comics), Marvel Comics character
- Jaghatai Khan, the Primarch of the White Scars Space Marines chapter in the fictional Warhammer 40,000 universe
- Kamal Khan, the main villain in the James Bond film Octopussy
- Kamal Khan, Mohammed Khan, two Pashtun characters in Rudyard Kipling's famous poem, The Ballad of East and West.
- Shere Khan, the tiger, in Rudyard Kipling's The Jungle Book, also adapted as a cartoon character in a famous Walt Disney Productions movie in 1967.
- Manga Khan, a DC Comics character
- Rizwan Khan, main character in the 2010 Bollywood film My Name Is Khan
- Shao Khan, the main antagonist in the Mortal Kombat video game series who is based on a typical Mongolian warlord
- Khan Noonien Singh, a prominent Star Trek villain in an original series episode and the principal antagonist in Star Trek II: The Wrath of Khan
- Haman Khan, a prominent Gundam villain in Mobile Suit Zeta Gundam and the principal antagonist in its sequel Mobile Suit Gundam ZZ; and his father Maharaja Khan
- 'Kubla Khan', poem by Samuel Taylor Coleridge, based loosely on the Mongol prince.
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