Keratin 14

Keratin 14

Identifiers Symbols KRT14; CK14; EBS3; EBS4; K14; NFJ External IDs OMIM: 148066 MGI: 96688 HomoloGene: 110439 GeneCards: KRT14 Gene

Gene Ontology
Molecular function • structural constituent of cytoskeleton
• protein binding
Cellular component • nucleus
• nucleolus
• cytoplasm
• mitochondrion
• cytosol
• intermediate filament
• keratin filament
• cell periphery
Biological process • epidermis development
• response to zinc ion
• response to ionizing radiation
• epithelial cell differentiation
• hemidesmosome assembly
• cell junction assembly
• intermediate filament bundle assembly
Sources: Amigo / QuickGO
RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 3861 16664 Ensembl ENSG00000186847 ENSMUSG00000045545 UniProt P02533 Q61781 RefSeq (mRNA) NM_000526.4 NM_016958.1 RefSeq (protein) NP_000517.2 NP_058654.1 Location (UCSC) Chr 17:
39.74 – 39.74 Mb Chr 11:
100.2 – 100.21 Mb PubMed search

Keratin, type I cytoskeletal 14 also known as cytokeratin-14 (CK-14) or keratin-14 (KRT14) is a protein that in humans is encoded by the KRT14 gene.

Keratin 14 is a type I keratin. It is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells.

Read more about Keratin 14:  Pathology