Research Interests
Kendall Houk's research focuses on theoretical and computational organic chemistry. His group is involved in developing rules to predict reactivity through a better understanding of organic reactions through computer modeling and experimental confirmation of predictions. He collaborates prodigiously with chemists all over the world. Among his current interests are the theoretical investigations and design of enzyme-catalyzed reactions, a collaboration that has recently led to the first successful design and synthesis of enzymes for non-natural reactions, the quantitative modeling of asymmetric reactions used in synthesis, the mechanisms and dynamics of pericyclic reactions and competing diradical processes, including a new theory of 1,3-dipolar cycloadditions, the mechanisms of organometallic reactions, and the molecular dynamics and reactions of hemicarcerands and other host-guest complexes. He has published over 700 articles in refereed journals and is among the 100 most-cited chemists. He is also a member of the California Nanosystems Institute.
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