Kain may refer to:
- Kain Department, a department in the Yatenga Province of Burkina Faso
- Mount Kain, a mountain in the Fraser River Valley of Mount Robson Provincial Park, Canada
- Kaïn, a folk rock group from Quebec
- Kain (Legacy of Kain), the protagonist of the Legacy of Kain series of videogames
- Kain (Tenchi Muyo!), a character from Tenchi Muyo! in Love
- Kain, an archetype in Fire Emblem
- Kain, a former municipality part of Tournai, Belgium
- KAIN-LP, a low-power television station (channel 55) licensed to Natchitoches, Louisiana, United States
- A former name for Qaen, Iran
Read more about Kain: People With The Given Name, People With The Surname