Kaempferia Galanga - Pharmacology

Pharmacology

The rhizomes of aromatic ginger have been reported to include cineol, borneol, 3-carene, camphene, kaempferol, kaempferide, cinnamaldehyde, p-methoxycinnamic acid, ethyl cinnamate and ethyl p-methoxycinnamate. Extracts of the plant using methanol have shown larvicidal activity against the second stage larvae of dog roundworms (Toxocara canis). It was also found to be effective as an amebicide in vitro against three species of Acanthamoeba, which cause granulomatous amebic encephalitis and amebic keratitis. In 1999, the rhizome extract was found to inhibit activity of Epstein-Barr virus. Further research has demonstrated the extract effectively kills larvae of the mosquito Culex quinquefasciatus and repels adult Aedes aegypti mosquitoes, both of which are serious disease vectors. As a result of these findings, research is underway to evaluate the plant extract's use as an insect repellent, with preliminary findings suggesting that it is not an irritant to the skin of rats.

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