Types
There are three ways of juxtacrine signaling:
- A ligand on the surface of a cell interacts with a receptor on an adjacent cell e.g.*Notch signalling.
- Ligand is in the extacellular matrix and is secreted by one cell to interact with anthor cell, the receptor in this case is integrin.
- A direct transmission of signals between adjacent cells that possess broad patches of closely apposed plasma membrane linked by transmembrane channels known as connexons. The gap between the cells can usually be between only 2 and 4 nm.
Read more about this topic: Juxtacrine Signalling
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