Achievements
Sambrook is best known for his studies on DNA tumor viruses and the molecular biology of normal and neoplastic cells. His Tumour Virus Group at Cold Spring Harbor identified and mapped all of the major genes of adenoviruses and SV40, determined their transcriptional control in infected and transformed cells, and elucidated the mechanism of integration of these viruses into the genome of the host cell. He has also made important contributions to the understanding of intracellular traffic and protein folding and is an influential leader in the field of the molecular genetics of human cancer.
Sambrook is Director of Research at the Peter MacCallum Cancer Centre in Melbourne and is an elected Fellow of the Australian Academy of Sciences and the Royal Society. He is the founder and director of the Kathleen Cunningham Consortium for research into familial breast cancer, KConFab, that was established in 1995.
Sambrook has published three editions of the best-selling, highly influential laboratory manual Molecular Cloning. He is also co-editor of Inspiring Science: Jim Watson and the Age of DNA and Life Illuminated: Selected Papers from Cold Spring Harbor Volume 2, 1972–1994. All three books were published by Cold Spring Harbor Laboratory Press.
In 2009 he was awarded the "Victorian Government Leadership and Innovation Award".
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