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- John Vaughan (East India Company officer) (1778–1830), British East India Company army officer
- John Vaughan (architect), American architect active in 1891 in Salt Lake City, Utah
- John Griffith Vaughan (1926-2005), British food scientist
- John Christian Vaughan, Australian historian and vexillographer
- Johnny Vaughan (born 1966), English broadcaster and journalist
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