John II Orsini, also John Komnenos Doukas or Comnenus Ducas (Greek: Ιωάννης Κομνηνός Δούκας, Iōannēs Komnēnos Doukas, Italian: Giovanni II Orsini), was count palatine of Cephalonia from 1323 to 1324 and Despot of Epirus from 1323 to 1335.
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