John Fitzpatrick or FitzPatrick may refer to:
- John Fitzpatrick (athlete) (1907–?), Canadian sprinter
- John FitzPatrick (Australian federal politician) (1915–1997), former Australian federal politician
- John Fitzpatrick (baseball) (1904–1990), coach and manager in Major League Baseball
- John Fitzpatrick (footballer) (born 1946), Scottish football (soccer) player
- John Fitzpatrick (Irish footballer), Irish soccer player during the 1890s
- John Fitzpatrick (New Orleans) (1844–1919), Irish-American mayor of New Orleans, Louisiana, United States in the 1890s
- John Fitzpatrick (New South Wales politician) (1862–1932), former New South Wales state politician
- John F. Fitzpatrick (publisher) (1887–1960), publisher of The Salt Lake Tribune from 1924 to 1960
- John Fitzpatrick (racing driver) (born 1943), winner of Norisring 200 Miles in 1984
- John Fitzpatrick (test pilot), test pilot and founder of the Society of Experimental Test Pilots
- John Fitzpatrick (unionist) (1871–1946), former leader of the Chicago Federation of Labor
- John Bernard Fitzpatrick (1812–1866), American Roman Catholic bishop
- John Lalor Fitzpatrick, Member of Parliament for Queen's County Ossory, 1916–1918
- Jack Fitzpatrick (businessman) (John Hitchcock Fitzpatrick, 1923–2011), American businessman and politician from Massachusetts
- John FitzPatrick, 1st Baron Castletown (1811–1883)
- John Joseph Fitzpatrick (1918–2006), American bishop
- John FitzPatrick, 1st Earl of Upper Ossory (1719–1758)
- John FitzPatrick, 2nd Earl of Upper Ossory (1745–1818), Irish peer and Member of Parliament