Janssen Pharmaceutica - Some Drugs Developed By Janssen Pharmaceutica

Some Drugs Developed By Janssen Pharmaceutica

R-code Name Brandname Synthetized Marketed
R5 ambucetamide Neomeritine 1953 1955
R79 isopropamide iodide Priamide-Janssen 1954 1955
R253 diisopromine Bilagol 1955 1956
R516 cinnarizine Stugeron 1955 1958
R875 dextromoramide Palfium 1955 1957
R1132 diphenoxylate Reasec 1956 1960
R1625 haloperidol Haldol 1958 1959
R2498 trifluperidol Triperidol 1959 1961
R3345 pipamperone Dipiperon 1960 1961
R3365 piritramide Dipidolor 1960 1967
R4263 fentanyl Fentanyl 1960 1963
R4584 benperidol Frenactyl 1961 1965
R4749 droperidol Dehydrobenzperidol 1961 1963
R4845 bezitramide Burgodin 1961 1971
R6218 fluspirilene Imap 1963 1971
R6238 pimozide Orap 1963 1970
R7904 lidoflazine Clinium 1964 1969
R11333 bromperidol Impromen 1966 1981
R12564 levamisole Ergamisol 1966 1969
R13672 haloperidol decanoate Haldol decanoas 1967 1981
R14889 miconazole nitrate Daktarin 1967 1971
R14950 flunarizine Sibelium 1967 1977
R15889 lorcainide Remivox 1968 1983
R16341 penfluridol Semap 1968 1973
R16470 dexetimide Tremblex 1968 1972
R16659 etomidate Hypnomidate 1964 1977
R17635 mebendazole Vermox 1968 1972
R18553 loperamide Imodium 1969 1973
R33800 sufentanil Sufenta 1974 1979
R33812 domperidone Motilium 1974 1978
R35443 oxatomide Tinset 1975 1981
R39209 alfentanil Rapifen 1976 1983
R33799 carfentanil Wildnil 1976 1980?
R41400 ketoconazole Nizoral 1976 1981
R43512 astemizole Hismanal 1977 1983
R46541 bromperidol decanoate Impromen decanoas 1978 1984
R49945 ketanserin tartrate Sufrexal 1980 1987
R30490 or R32395 lofentanil ? 1980? ?
R50547 levocabastine Livostin 1979 1989
R51211 itraconazole Sporanox 1980 1986
R51619 cisapride Prepulsid 1980 1989
R64766 risperidone Risperdal 1984 1993

Janssen Pharmaceuticals has developed and brought to the market about 70 new active substances (NCE), of which the most well-known are (name may differ):

  • Imodium (against diarrhoea. Active substance: loperamide)
  • Motilium (against flatulence — and bowel impairments. Active substance: domperidone)
  • Reminyl (against Alzheimer's disease (dementia). Active substance: galantamine)
  • Daktarin (against fungal infections. Active substance: miconazole)
  • Nizoral (against dandruff, Active substance: ketoconazole)
  • Durogesic (fentanyl patch for pain suppression. Active substance: fentanyl)
  • Vermox (against worms. Active substance: mebendazole)
  • Risperdal (antipsychotic, against mental illness such as schizophrenia. Active substance: risperidone)

Five drugs of Janssen Pharmaceuticals have been included on the WHO Model List of Essential Medicines:

  • Haldol (haloperidol)
  • Ergamisol (levamisole)
  • Daktarin (miconazole)
  • Vermox (mebendazole)
  • Nizoral (ketoconazole) (on the WHO list until 2005)

R207910 is an experimental diarylquinoline anti-tuberculosis drug, discovered by Koen Andries and his team, which promises a shorter and simpler treatment for Tuberculosis (TB).

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