Some Drugs Developed By Janssen Pharmaceutica
| R-code | Name | Brandname | Synthetized | Marketed |
| R5 | ambucetamide | Neomeritine | 1953 | 1955 |
| R79 | isopropamide iodide | Priamide-Janssen | 1954 | 1955 |
| R253 | diisopromine | Bilagol | 1955 | 1956 |
| R516 | cinnarizine | Stugeron | 1955 | 1958 |
| R875 | dextromoramide | Palfium | 1955 | 1957 |
| R1132 | diphenoxylate | Reasec | 1956 | 1960 |
| R1625 | haloperidol | Haldol | 1958 | 1959 |
| R2498 | trifluperidol | Triperidol | 1959 | 1961 |
| R3345 | pipamperone | Dipiperon | 1960 | 1961 |
| R3365 | piritramide | Dipidolor | 1960 | 1967 |
| R4263 | fentanyl | Fentanyl | 1960 | 1963 |
| R4584 | benperidol | Frenactyl | 1961 | 1965 |
| R4749 | droperidol | Dehydrobenzperidol | 1961 | 1963 |
| R4845 | bezitramide | Burgodin | 1961 | 1971 |
| R6218 | fluspirilene | Imap | 1963 | 1971 |
| R6238 | pimozide | Orap | 1963 | 1970 |
| R7904 | lidoflazine | Clinium | 1964 | 1969 |
| R11333 | bromperidol | Impromen | 1966 | 1981 |
| R12564 | levamisole | Ergamisol | 1966 | 1969 |
| R13672 | haloperidol decanoate | Haldol decanoas | 1967 | 1981 |
| R14889 | miconazole nitrate | Daktarin | 1967 | 1971 |
| R14950 | flunarizine | Sibelium | 1967 | 1977 |
| R15889 | lorcainide | Remivox | 1968 | 1983 |
| R16341 | penfluridol | Semap | 1968 | 1973 |
| R16470 | dexetimide | Tremblex | 1968 | 1972 |
| R16659 | etomidate | Hypnomidate | 1964 | 1977 |
| R17635 | mebendazole | Vermox | 1968 | 1972 |
| R18553 | loperamide | Imodium | 1969 | 1973 |
| R33800 | sufentanil | Sufenta | 1974 | 1979 |
| R33812 | domperidone | Motilium | 1974 | 1978 |
| R35443 | oxatomide | Tinset | 1975 | 1981 |
| R39209 | alfentanil | Rapifen | 1976 | 1983 |
| R33799 | carfentanil | Wildnil | 1976 | 1980? |
| R41400 | ketoconazole | Nizoral | 1976 | 1981 |
| R43512 | astemizole | Hismanal | 1977 | 1983 |
| R46541 | bromperidol decanoate | Impromen decanoas | 1978 | 1984 |
| R49945 | ketanserin tartrate | Sufrexal | 1980 | 1987 |
| R30490 or R32395 | lofentanil | ? | 1980? | ? |
| R50547 | levocabastine | Livostin | 1979 | 1989 |
| R51211 | itraconazole | Sporanox | 1980 | 1986 |
| R51619 | cisapride | Prepulsid | 1980 | 1989 |
| R64766 | risperidone | Risperdal | 1984 | 1993 |
Janssen Pharmaceuticals has developed and brought to the market about 70 new active substances (NCE), of which the most well-known are (name may differ):
- Imodium (against diarrhoea. Active substance: loperamide)
- Motilium (against flatulence — and bowel impairments. Active substance: domperidone)
- Reminyl (against Alzheimer's disease (dementia). Active substance: galantamine)
- Daktarin (against fungal infections. Active substance: miconazole)
- Nizoral (against dandruff, Active substance: ketoconazole)
- Durogesic (fentanyl patch for pain suppression. Active substance: fentanyl)
- Vermox (against worms. Active substance: mebendazole)
- Risperdal (antipsychotic, against mental illness such as schizophrenia. Active substance: risperidone)
Five drugs of Janssen Pharmaceuticals have been included on the WHO Model List of Essential Medicines:
- Haldol (haloperidol)
- Ergamisol (levamisole)
- Daktarin (miconazole)
- Vermox (mebendazole)
- Nizoral (ketoconazole) (on the WHO list until 2005)
R207910 is an experimental diarylquinoline anti-tuberculosis drug, discovered by Koen Andries and his team, which promises a shorter and simpler treatment for Tuberculosis (TB).
Read more about this topic: Janssen Pharmaceutica
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