James Spence may refer to:
- James Calvert Spence (1892–1954), pediatrician
- James Spence (surgeon) (1812–1882), Scottish surgeon
- James Houston Spence (1867–1939), Canadian lawyer and Senator
Famous quotes containing the word james:
“There are moods in which one feels the impulse to enter a tacit protest against too gross an appetite for pure aesthetics in this starving and sinning world. One turns half away, musingly, from certain beautiful useless things.”
—Henry James (1843–1916)