Jaffrey may refer to:
In places:
- Jaffrey, New Hampshire, USA
In people (with name of British origin):
- Sir Thomas Jaffrey 1st Baronet (1861–1953), Scottish actuary and a prominent citizen of Aberdeen
In people (with name as spelling of Jafri):
- Madhur Jaffrey (b. 1933), Indian actress and food writer
- Saeed Jaffrey (b. 1929), Indian actor
- Jaaved Jaffrey (b. 1963), Indian actor and comedian