IWE may refer to:
- Indian Writing in English
- International Worship in English, a Christian ministry of American missionary to South Korea, Bill Majors
- International Wrestling Enterprise, the public name of International Pro Wrestling, a professional wrestling promotion in Japan which operated from 1966 to 1981
- "IWE", the first single from What's the Time Mr Wolf? by the UK indie rock band Noisettes
- International Welding Engineer