Enzyme Mechanism
IPP isomerase catalyzes the isomerization of IPP to DMAPP by an antarafacial transposition of hydrogen. The empirical evidence suggests that this reaction proceeds by a protonation/deprotonation mechanism, with the addition of a proton to the re-face of the inactivated C3-C4 double bond resulting in a transient carbocation intermediate. The removal of the pro-R proton from C2 forms the C2-C3 double bond of DMAPP.
Read more about this topic: Isopentenyl-diphosphate Delta Isomerase
Famous quotes containing the word mechanism:
“I’ve never known a Philadelphian who wasn’t a downright “character;” possibly a defense mechanism resulting from the dullness of their native habitat.”
—Anita Loos (1888–1981)