Interzone may refer to:
- International zone, such as in Tangiers
- Interzone (book), the title of a short story collection by William Burroughs; it is also a setting in his 1959 novel Naked Lunch
- Interzone (magazine), a British science fiction magazine
- Interzone Entertainment, a computer games company
In music
- Interzone (band), a German blues/rock band
- Interzone a French/Syrian duet ( electric guitar/oud)
- "Atlantis to Interzone", a track on the Klaxons album Myths of the Near Future
- "Interzone", a track on the Joy Division album Unknown Pleasures
- "Interzone", the first track on the album The Interzone Mantras by Canadian band "The Tea Party"
- "Interzone", an album by John Zorn
In cinema
- Interzone (film), a 1987 film directed by Deran Sarafian