MHC and Sexual Mating
It has been suggested that MHC plays a role in the selection of potential mates, via olfaction. MHC genes make molecules that enable the immune system to recognize invaders; generally, the more diverse the MHC genes of the parents, the stronger the immune system of the offspring. It would therefore be beneficial to have evolved systems of recognizing individuals with different MHC genes and preferentially selecting them to breed with.
Yamazaki et al. (1976) showed this to be the case for male mice, which show a preference for females of different MHC. Similar results have been obtained with fish.
In 1995, Swiss biologist Claus Wedekind determined MHC influences both body odors and body odor preferences in humans, and that the women's preferences depend on their hormonal status. In an experiment, a group of female college students smelled T-shirts that had been worn by male students for two nights, without deodorant, cologne or scented soaps. Overwhelmingly, the women preferred the odors of men with dissimilar MHCs to their own. However, their preference was reversed if they were taking oral contraceptives. The hypothesis is that MHCs affect mate choice and that oral contraceptives can interfere with the preference for variation. A study in 2005 on 58 test subjects confirmed that taking oral contraceptives made women prefer men with MHCs similar to their own. Several follow up studies have confirmed the belief that paternally inherited HLA-associated odors influence odor preference and may serve as social cues. In 2008, Peter Donnelly and colleagues proposed that MHC is related to mating choice in some human populations.
Read more about this topic: Interpersonal Compatibility
Famous quotes containing the word mating:
“The elephant, not only the largest but the most intelligent of animals, provides us with an excellent example. It is faithful and tenderly loving to the female of its choice, mating only every third year and then for no more than five days, and so secretly as never to be seen, until, on the sixth day, it appears and goes at once to wash its whole body in the river, unwilling to return to the herd until thus purified. Such good and modest habits are an example to husband and wife.”
—St. Francis De Sales (1567–1622)