Clinical Significance
Interleukin-8 is often associated with inflammation. As an example, it has been cited as a proinflammatory mediator in gingivitis and psoriasis.. The fact that Interleukin-8 secretion is increased by oxidant stress, which thereby causes the recruitment of inflammatory cells induces a further increase in oxidant stress mediators, making it a key parameter in localized inflammation.
If a pregnant mother has high levels of interleukin-8, there is an increased risk of schizophrenia in her offspring. High levels of Interleukin 8 have been shown to reduce the likelihood of positive responses to antipsychotic medication in schizophrenia.
Read more about this topic: Interleukin 8
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“For a parent, it’s hard to recognize the significance of your work when you’re immersed in the mundane details. Few of us, as we run the bath water or spread the peanut butter on the bread, proclaim proudly, “I’m making my contribution to the future of the planet.” But with the exception of global hunger, few jobs in the world of paychecks and promotions compare in significance to the job of parent.”
—Joyce Maynard (20th century)