Tissue Expression
The IL-5 gene is located on chromosome 11 (in the mouse, chromosome 5 in humans) in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Interleukin-5 is also expressed by eosinophils and has been observed in the mast cells of asthmatic airways by immunohistochemistry. IL-5 expression is regulated by several transcription factors including GATA3.
Read more about this topic: Interleukin 5
Famous quotes containing the words tissue and/or expression:
“Whether or not his newspaper and a set of senses reduced to five are the main sources of the so-called “real life” of the so- called average man, one thing is fortunately certain: namely, that the average man himself is but a piece of fiction, a tissue of statistics.”
—Vladimir Nabokov (1899–1977)
“Our minds can go no further. The human imagination is capable of no further expression of beauty than the carved owl of Athene, the archaic, marble serpent, the arrogant selfish head of the Acropolis Apollo.”
—Hilda Doolittle (1886–1961)