Interleukin 17 - Therapeutic Target

Therapeutic Target

Because of its involvement in autoimmune conditions, IL-17 inhibitors are being investigated as possible treatments, e.g. vidofludimus in phase IIB for rheumatoid arthritis, psoriasis and inflammatory bowel disease. As of early 2012, clinical trials of IL-17 antibodies against psoriasis have shown extremely promising results in Phase II. IL-17 has also been implicated in multiple sclerosis. The anti-IL-23 antibody ustekinumab can be used to effectively treat psoriasis by reducing IL-17.

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