Composition
Interferon alfa contains a mixture of several proteins, all with structural, serological, and functional properties typical for natural interferon alpha (IFN α). The major subtypes identified are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated. The IFN-α content is expressed in International Units per milliliter, and the drug product is formulated in isotonic phosphate buffer solution at pH = 7.2, and supplemented with human albumin at 1.5 milligrams per milliliter. The albumin used is a medicinal product approved in several countries, and is indicated for subcutaneous injection therapy.
Read more about this topic: Interferon Alfa
Famous quotes containing the word composition:
“Vices enter into the composition of virtues as poisons into the composition of certain medicines. Prudence and common sense mix them together, and make excellent use of them against the misfortunes that attend human life.”
—François, Duc De La Rochefoucauld (1613–1680)
“At painful times, when composition is impossible and reading is not enough, grammars and dictionaries are excellent for distraction.”
—Elizabeth Barrett Browning (1806–1861)
“There was not a grain of poetry in the whole composition of Lord Fawn, and poetry was what her very soul craved;Mpoetry, together with houses, champagne, jewels, and admiration.”
—Anthony Trollope (1815–1882)