Integrase Inhibitor - Drugs Under Development

Drugs Under Development

  • Elvitegravir (GS 9137 or JTK-303), licensed by Gilead Sciences from Japan Tobacco, is currently undergoing Phase 3 clinical trials. GS 9137 is a low-molecular-weight, highly selective integrase inhibitor that shares the core structure of quinolone antibiotics.
  • MK-2048, a second generation integrase inhibitor, that appears to have a duration of action up to 4 times longer than raltegravir.

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