Insulin Tolerance Test - Contraindications

Contraindications

• This test should not be performed on children outside a specialist pediatric endocrine unit
• Ischemic heart disease
• Epilepsy
• Severe panhypopituitarism, hypoadrenalism
• Hypothyroidism impairs the GH and cortisol response. Patients should have corticosteroid replacement commenced prior to thyroxine as the latter has been reported to precipitate an Addisonian crisis with dual deficiency. If adrenal insufficiency is confirmed, the need for a repeat ITT may need to be reconsidered after 3 months thyroxine therapy.