Decline
Insulin coma therapy was used in most hospitals in the United States and the United Kingdom during the 1940s and 1950s, but the numbers of patients were restricted by the requirement for intensive medical and nursing supervision and the length of time it took to complete a course of treatment. For example at one typical large British psychiatric hospital, Severalls Hospital in Essex, insulin coma treatment was given to 39 patients in 1956. The same year 18 patients received modified insulin treatment, whilst 432 patients were given electroconvulsive treatment.
In 1953 British psychiatrist Harold Bourne published a paper entitled "The insulin myth" in the Lancet, in which he argued that there was no sound basis for believing that insulin coma therapy counteracted the schizophrenic process in a specific way. If treatment worked, he said, it was because patients were chosen for their good prognosis and were given special treatment: "insulin patients tend to be an elite group sharing common privileges and perils".
In 1957, when insulin coma treatment use was already declining, the Lancet published the results of a randomized, controlled trial where patients were either given insulin coma treatment or identical treatment but with unconsciousness produced by barbiturates. There was no difference in outcome between the groups and the authors concluded that, whatever the benefits of the coma regime, insulin was not the specific therapeutic agent.
Read more about this topic: Insulin Shock Therapy
Famous quotes containing the word decline:
“I heard a Californian student in Heidelberg say, in one of his calmest moods, that he would rather decline two drinks than one German adjective.”
—Mark Twain [Samuel Langhorne Clemens] (1835–1910)
“Reckoned physiologically, everything ugly weakens and afflicts man. It recalls decay, danger, impotence; he actually suffers a loss of energy in its presence. The effect of the ugly can be measured with a dynamometer. Whenever man feels in any way depressed, he senses the proximity of something “ugly.” His feeling of power, his will to power, his courage, his pride—they decline with the ugly, they increase with the beautiful.”
—Friedrich Nietzsche (1844–1900)
“But only that soul can be my friend which I encounter on the line of my own march, that soul to which I do not decline, and which does not decline me, but, native of the same celestial latitude, repeats in its own all my experience.”
—Ralph Waldo Emerson (1803–1882)