Gene Ontology | |
---|---|
Molecular function | • IMP cyclohydrolase activity • phosphoribosylaminoimidazolecarboxamide formyltransferase activity • protein homodimerization activity |
Cellular component | • mitochondrion • cytosol |
Biological process | • nucleobase-containing compound metabolic process • purine nucleobase metabolic process • 'de novo' IMP biosynthetic process • purine ribonucleoside monophosphate biosynthetic process • organ regeneration • small molecule metabolic process • nucleobase-containing small molecule metabolic process |
Sources: Amigo / QuickGO |
216.18 – 216.21 Mb
71.56 – 71.58 Mb
Bifunctional purine biosynthesis protein PURH is a protein that in humans is encoded by the ATIC gene.
ATIC encodes an enzyme which generates inosine monophosphate from aminoimidazole carboxamide ribonucleotide.
It has two functions:
- EC 2.1.2.3 - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase
- EC 3.5.4.10 - IMP cyclohydrolase
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