Treatment
Unfortunately, an efficient prevention of the disease by vaccination is not possible, although several studies identified potential vaccine candidate proteins, i.e. i-antigens, of the parasite.
Any treatment method must take into account the species of fish (some will not tolerate certain medications), how high the infection rate is, and the size and type of environment.
If it is detected before it becomes too serious, a number of different treatments can be applied. Only the free-swimming stage of the parasite is susceptible to treatment; neither the trophonts under the epithelium nor the tomont cysts can be killed.
Read more about this topic: Ichthyophthirius Multifiliis
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—C. John Sommerville (20th century)