Effect of Size
Size may be a factor in determining hypoallergenicity. It is possible that the total body surface area of the dog is more indicative of reduced production of allergens than its breed.
Smaller dogs will also leave fewer environmental pollutants containing dog dander and dog allergens (reduced fecal matter, urine and saliva). Small hairless dogs may be less likely to cause allergic reactions "because it's so easy to bathe them and the dander falls off them." Dogs may leave behind urine, saliva and fecal matter as allergen sources. Dogs with access to the outdoors may introduce outdoor allergens such as mold and pollen with larger animals tracking in more of these allergens. It is well established that most individuals with dog allergy also suffer with additional environmental allergies. Individuals with dog allergy may also be at increased risk for human protein hypersensitivity with cross-reactivity of dog dander allergen and human seminal fluid.
Read more about this topic: Hypoallergenic Dog Breed
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