Improving Cell Survival
Among the approaches aimed at improving cell survival in the presence of mutant huntingtin are correction of transcriptional regulation using histone deacetylase inhibitors, modulating aggregation of huntingtin, improving metabolism and mitochondrial function and restoring dysfunction of synapses.
Read more about this topic: Huntington's Disease Clinical Research
Famous quotes containing the words improving, cell and/or survival:
“She was so overcome by the splendor of his achievement that she took him into the closet and selected a choice apple and delivered it to him, along with an improving lecture upon the added value and flavor a treat took to itself when it came without sin through virtuous effort. And while she closed with a Scriptural flourish, he “hooked” a doughnut.”
—Mark Twain [Samuel Langhorne Clemens] (1835–1910)
“There’s not one part of his physical being that’s like that of human beings. From his warped brain down to the tiniest argumentative cell of his huge carcass, he’s unearthly.”
—Willis Cooper. Rowland V. Lee. Wolf von Frankenstein (Basil Rathbone)
“We never stop investigating. We are never satisfied that we know enough to get by. Every question we answer leads on to another question. This has become the greatest survival trick of our species.”
—Desmond Morris (b. 1928)