Prevention
Despite decades of research, no vaccines currently exist.
Recombinant technology has however been used to target the formation of vaccines for hPIV-1, 2 and 3 serotypes and has taken the form of several live-attenuated intranasal vaccines. Two vaccines in particular were found to be immunogenic and well tolerated against hPIV-3 in phase I trials. hPIV 1 and 2 vaccine candidates remain less advanced.
Vaccine techniques which have been used against hPIV are not limited to intranasal forms, but also viruses attenuated by cold passage, host range attenuation, chimeric construct vaccines and also introducing mutations with the help of reverse genetics to achieve attenuation.
Maternal antibodies may offer some degree of protection against hPIV during the early stages of life via the colostrum in breast milk.
Read more about this topic: Human Parainfluenza Viruses
Famous quotes containing the word prevention:
“... if this world were anything near what it should be there would be no more need of a Book Week than there would be a of a Society for the Prevention of Cruelty to Children.”
—Dorothy Parker (1893–1967)