Blood Group Systems
| ISBT № | System name | System symbol | Epitope or carrier, notes | Chromosome |
|---|---|---|---|---|
| 001 | ABO | ABO | Carbohydrate (N-Acetylgalactosamine, galactose). A, B and H antigens mainly elicit IgM antibody reactions, although anti-H is very rare, see the Hh antigen system (Bombay phenotype, ISBT #18). | 9 |
| 002 | MNS | MNS | GPA / GPB (glycophorins A and B). Main antigens M, N, S, s. | 4 |
| 003 | P | P1 | Glycolipid. Antigen P1. | 22 |
| 004 | Rh | RH | Protein. C, c, D, E, e antigens (there is no "d" antigen; lowercase "d" indicates the absence of D). | 1 |
| 005 | Lutheran | LU | Protein (member of the immunoglobulin superfamily). Set of 21 antigens. | 19 |
| 006 | Kell | KEL | Glycoprotein. K1 can cause hemolytic disease of the newborn (anti-Kell), which can be severe. | 7 |
| 007 | Lewis | LE | Carbohydrate (fucose residue). Main antigens Lea and Leb - associated with tissue ABH antigen secretion. | 19 |
| 008 | Duffy | FY | Protein (chemokine receptor). Main antigens Fya and Fyb. Individuals lacking Duffy antigens altogether are immune to malaria caused by Plasmodium vivax and Plasmodium knowlesi. | 1 |
| 009 | Kidd | dbMHC | Protein (urea transporter). Main antigens Jka and Jkb. | 18 |
| 010 | Diego | DI | Glycoprotein (band 3, AE 1, or anion exchange). Positive blood is found only among East Asians and Native Americans. | 17 |
| 011 | Yt or Cartwright | YT | Protein (AChE, acetylcholinesterase). | 7 |
| 012 | XG | XG | Glycoprotein. | X |
| 013 | Scianna | SC | Glycoprotein. | 1 |
| 014 | Dombrock | DO | Glycoprotein (fixed to cell membrane by GPI, or glycosyl-phosphatidyl-inositol). | 12 |
| 015 | Colton | CO | Aquaporin 1. Main antigens Co(a) and Co(b). | 7 |
| 016 | Landsteiner-Wiener | LW | Protein (member of the immunoglobulin superfamily). | 19 |
| 017 | Chido/Rodgers | CH/RG | C4A C4B (complement fractions). | 6 |
| 018 | Hh/Bombay | H | Carbohydrate (fucose residue). | 19 |
| 019 | Kx | XK | Glycoprotein. | X |
| 020 | Gerbich | GE | GPC / GPD (Glycophorins C and D). | 2 |
| 021 | Cromer | CROM | Glycoprotein (DAF or CD55, regulates complement fractions C3 and C5, attached to the membrane by GPI). | 1 |
| 022 | Knops | KN | Glycoprotein (CR1 or CD35, immune complex receptor). | 1 |
| 023 | Indian | IN | Glycoprotein (CD44 adhesion function?). | 11 |
| 024 | Ok | OK | Glycoprotein (CD147). | 19 |
| 025 | Raph | MER2 | Transmembrane glycoprotein. | 11 |
| 026 | JMH | JMH | Protein (fixed to cell membrane by GPI). | 6 |
| 027 | Ii | I | Branched (I) / unbranched (i) polysaccharide. | 6 |
| 028 | Globoside | GLOB | Glycolipid. Antigen P. | 3 |
| 029 | GIL | GIL | Aquaporin 3. | 9 |
| 030 | Rh-associated glycoprotein | RHAG | Rh-associated glycoprotein. | 6 |
| Langereis | LAN | ABCB6. Porphyrin transporter | 2 | |
| Junior | JR | ABCG2. Multi-drug transporter protein | 4 |
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