Huang Minglon - Huang-Minlon Modification

The Huang Modification or Huang-Minlon Modification is named after Huang Minglon. It was the first time that a Chinese name appeared in an organic chemical reaction.

It's a short-cut for the Wolff-Kishner reduction and involves heating the carbonyl compound, potassium hydroxide, and hydrazine hydrate together in ethylene glycol in a one-pot reaction. Huang devised this modified synthesis in 1945 while he was in the United States.

In many sources, it's also mentioned such method as Wolff-Kishner-Huang Reduction (or Wolff-Kishner-Huang Minglon method/reaction/reduction), or in German Wolff-Kishner/Huang-Minlon Reduktion (or Wolff-Kishner-Huang-Minlon-Reduktion).

In some sources, people think Huang and Minlon are two different persons. It's in fact a mistake, Huang is his family name and Minlon is his first name. Huang Minglon is the Wade-Giles spelling, and Huang Minglong is its Pinyin romanization of the Chinese characters in his name.

Read more about this topic:  Huang Minglon