HSN2 - Function

Function

The WNK1/HSN2 isoforms are expressed in the sensory parts of the peripheral nervous system and central nervous system which are associated with the transmission of sensory and nociceptive signals. These parts include satellite cells, Schwann cells, and sensory neurons. The novel protein product of the isoform is more plentiful in sensory neurons than motor neurons. It is proposed that this gene product may play a role in the development and/or maintenance of peripheral sensory neurons or their supporting Schwann cells.

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