Singles
- "Over My Head (Cable Car)" was released as the first single from the album, and it became a top 40 hit on the Modern Rock Tracks chart in late 2005. It lasted three weeks on the chart and peaked at position #37. The song peaked at #8 on the Billboard Hot 100 chart. On the Billboard Adult Top 40 chart, the single reached the #2 position. Internationally, the song was a Top 25 hit in Australia, Canada, Denmark, Ireland, New Zealand and the UK. The song was the fifth-most downloaded single of 2006.
- "How to Save a Life" was released as the second single from the album. The song reached the top three of the Billboard Hot 100 chart, surpassing the peak position of "Over My Head (Cable Car)". It became the joint sixth longest charting single of all time on the Billboard Hot 100, tying with Santana's "Smooth", at 58 consecutive weeks. The song also topped the Adult Top 40 chart for 15 consecutive weeks. "How to Save a Life" became a major hit internationally, topping the singles chart in Ireland, Spain and Canada. The song also charted in the top five in Australia, Italy, Sweden and in the UK Singles Chart.
- "Look After You" was released as the band's third single; the song peaked at position 59 in the Billboard Hot 100, becoming the band's first single to miss the Top 40. The song peaked at #49 on Billboard Pop 100 and at #12 on the Hot Adult Top 40 Tracks.
- "All at Once" was released as the fourth and final single from the album. It peaked at #20 on the Hot Adult Top 40 Tracks chart.
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