A Hoogsteen base pair is a variation of base-pairing in nucleic acids such as the A•T pair. In this manner, two nucleobases on each strand can be held together by hydrogen bonds in the major groove. A Hoogsteen base pair applies the N7 position of the purine base (as a hydrogen bond acceptor) and C6 amino group (as a donor), which bind the Watson-Crick (N3–N4) face of the pyrimidine base.
Read more about Hoogsteen Base Pair: History, Chemical Properties, Triplex Structures, Quadruplex Structures, Triple Helix Base Pairing
Famous quotes containing the words base and/or pair:
“I think it is worse to be poor in mind than in purse, to be stunted and belittled in soul, made a coward, made a liar, made mean and slavish, accustomed to fawn and prevaricate, and “manage” by base arts a husband or a father,—I think this is worse than to be kicked with hobnailed shoes.”
—Frances Power Cobbe (1822–1904)
“I should have been a pair of ragged claws
Scuttling across the floors of silent seas.”
—T.S. (Thomas Stearns)