A Hoogsteen base pair is a variation of base-pairing in nucleic acids such as the A•T pair. In this manner, two nucleobases on each strand can be held together by hydrogen bonds in the major groove. A Hoogsteen base pair applies the N7 position of the purine base (as a hydrogen bond acceptor) and C6 amino group (as a donor), which bind the Watson-Crick (N3–N4) face of the pyrimidine base.
Read more about Hoogsteen Base Pair: History, Chemical Properties, Triplex Structures, Quadruplex Structures, Triple Helix Base Pairing
Famous quotes containing the words base and/or pair:
“Report of fashions in proud Italy,
Whose manners still our tardy-apish nation
Limps after in base imitation.”
—William Shakespeare (1564–1616)
“You are always looking for already-felt emotions, just as you like to get an old pair of trousers back from the cleaners, which seem new when you don’t look too closely. Artists are cleaners, don’t let yourself be taken in by them. True modern works of art are made not by artists but quite simply by men.”
—Francis Picabia (1878–1953)