A Hoogsteen base pair is a variation of base-pairing in nucleic acids such as the A•T pair. In this manner, two nucleobases on each strand can be held together by hydrogen bonds in the major groove. A Hoogsteen base pair applies the N7 position of the purine base (as a hydrogen bond acceptor) and C6 amino group (as a donor), which bind the Watson-Crick (N3–N4) face of the pyrimidine base.
Read more about Hoogsteen Base Pair: History, Chemical Properties, Triplex Structures, Quadruplex Structures, Triple Helix Base Pairing
Famous quotes containing the words base and/or pair:
“The worst of my actions or conditions seem not so ugly unto me as I find it both ugly and base not to dare to avouch for them.”
—Michel de Montaigne (1533–1592)
“... the Ovarian Theory of Literature, or, rather, its complement, the Testicular Theory. A recent camp follower ... of this explicit theory is ... Norman Mailer, who has attributed his own gift, and the literary gift in general, solely and directly to the possession of a specific pair of organs. One writes with these organs, Mailer has said ... and I have always wondered with what shade of ink he manages to do it.”
—Cynthia Ozick (b. 1928)