A Hoogsteen base pair is a variation of base-pairing in nucleic acids such as the A•T pair. In this manner, two nucleobases on each strand can be held together by hydrogen bonds in the major groove. A Hoogsteen base pair applies the N7 position of the purine base (as a hydrogen bond acceptor) and C6 amino group (as a donor), which bind the Watson-Crick (N3–N4) face of the pyrimidine base.
Read more about Hoogsteen Base Pair: History, Chemical Properties, Triplex Structures, Quadruplex Structures, Triple Helix Base Pairing
Famous quotes containing the words base and/or pair:
“Jealousy is both reasonable and belongs to reasonable men, while envy is base and belongs to the base, for the one makes himself get good things by jealousy, while the other does not allow his neighbour to have them through envy.”
—Aristotle (384–322 B.C.)
“The majority of persons choose their wives with as little prudence as they eat. They see a trull with nothing else to recommend her but a pair of thighs and choice hunkers, and so smart to void their seed that they marry her at once. They imagine they can live in marvelous contentment with handsome feet and ambrosial buttocks. Most men are accredited fools shortly after they leave the womb.”
—Edward Dahlberg (1900–1977)