Human Pathology
Accumulation of excess homogentisic acid and its oxide, named alkapton, is a result of the failure of the enzyme homogentisic acid 1,2-dioxygenase (typically due to a mutation) in the degradative pathway of tyrosine, consequently associated with alkaptonuria.
Read more about this topic: Homogentisic Acid
Famous quotes containing the words human and/or pathology:
“The greatest sweetener of human life is Friendship. To raise this to the highest pitch of enjoyment, is a secret which but few discover.”
—Joseph Addison (1672–1719)
“It is often said that Poland is a country where there is anti-semitism and no Jews, which is pathology in its purest state.”
—Bronislaw Geremek (b. 1932)