Homeodomain Fold - Dlx Proteins

Dlx Proteins

Further information: Dlx (gene)

Vertebrates have six genes from the Dlx family of homeodomain transcription factors, arranged into three clusters: Dlx1/Dlx2, Dlx3/Dlx4 and Dlx5/Dlx6. All six are homologs of the fly gene Distal-less. Dlx genes are involved in the development of the nervous system and of limbs.

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