Hodgkinson is an Anglo-Saxon surname, and may refer to:
- Alan Hodgkinson, English footballer
- Albert Hodgkinson, English recipient of the Distinguished Conduct Medal
- Alison Hodgkinson, South African cricketer
- Antony Hodgkinson, English drummer
- Bert Hodgkinson (1884–1939), Welsh international footballer
- Bert Hodgkinson (footballer born 1903), English footballer
- Charles Hodgkinson, English footballer
- Clement Hodgkinson, English naturalist
- Colin Hodgkinson, British musician
- Derek Hodgkinson, British World War II pilot
- Eaton Hodgkinson, English engineer
- Frank Hodgkinson, Australian artist
- George Langton Hodgkinson, English priest and cricketer
- Gerard Hodgkinson, English cricketer
- Gilbert Hodgkinson, English cricketer
- Greta Hodgkinson, Canadian ballet dancer
- Grosvenor Hodgkinson, English lawyer and politician
- Harry Hodgkinson (footballer), English footballer
- Harry Hodgkinson (writer), English writer
- John Hodgkinson (footballer), English footballer
- Katrina Hodgkinson, Australian politician
- Patrick Hodgkinson, English architect
- Randall Hodgkinson, American pianist
- Richard Hodgkinson, English cricketer
- Roland Hodgkinson, first chief of police, Newport Beach, California, from 1928 - 1953
- Samuel Hodgkinson, New Zealand politician
- Sandra Hodgkinson, American lawyer
- Simon Hodgkinson, English rugby player
- Tim Hodgkinson, English musician and composer
- Tom Hodgkinson, English writer and editor
- Toni Hodgkinson, New Zealand athlete
- Will Hodgkinson, English journalist and author
- William Hodgkinson, Welsh footballer, brother of Bert Hodgkinson