Serology
| DQB1* | DQ5 | DQ1 | DQ6 | Sample |
| allele | % | % | % | size (N) |
| *0501 | 69 | 20 | 2 | 5536 |
| *0502 | 48 | 24 | 15 | 919 |
| *0503 | 58 | 22 | 4 | 1327 |
| *0504 | 59 | 17 | 2 | 48 |
| Red indicates the level of 'false' reaction in non-DQ5 serotypes | ||||
The efficiency of DQ1 recognition relative to DQ5 and DQ6 is listed above. Since DQ1 recognizes alpha, the DQ5 and DQ6 recognition are to beta chain. Meaning that DQ1 is corecognized with DQ5 and DQ6. Efficient recognition of a genotyped allele approaches 100%. Compared to DQ2 serotyping of DQB1*0201 positive individuals (98%), the efficiency of DQ5 recognition is relatively low and error prone.
While DQ5 recognizes DQB1*05 alleles more efficiently than DQ1, the serotyping is rather poor method of typing for transplantation or disease association prediction or study.
Read more about this topic: HLA-DQ5