High Sierra

High Sierra may refer to:

• High Sierra (biome), a region of California
• Sierra Nevada (U.S.), a mountain range in California also called the High Sierra or High Sierras
  • High Sierra Trail, a hiking trail which crosses the Sierra Nevada
• High Sierra (film), a 1941 film starring Humphrey Bogart and Ida Lupino
• High Sierra Music Festival, an annual music festival held in Quincy, California
• High Sierra Format, an early CD-ROM filesystem
• High Sierra Sport, a sporting company