High Altitude Pulmonary Edema - Research

Research

In order to help understand the factors that make some individuals susceptible to HAPE, the International HAPE Database was set up in 2004. Individuals who have previously suffered from HAPE can register with this confidential database in order to help researchers study the condition. The standard and most important treatment is to descend to lower altitude as quickly as possible, preferably by at least 1000 metres. Oxygen should also be given if possible. Symptoms tend to quickly improve with descent, but more severe symptoms may continue for several days. The standard drug treatments for which there is strong clinical evidence are dexamethasone. and nifedipine Phosphodiesterase inhibitors such as tadalafil are also effective but may worsen the headache of mountain sickness.

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