Role in Disease
The existence of HMWK was hypothesised in the 1970s when several patients were described with a deficiency of a class of plasma protein and a prolonged bleeding time and partial thromboplastin time (PTT).
As in deficiency of the associated Hageman factor, there is no increased risk of bleeding.Read more about this topic: High-molecular-weight Kininogen
Famous quotes containing the words role and/or disease:
“Our role is to support anything positive in black life and destroy anything negative that touches it. You have no other reason for being. I don’t understand art for art’s sake. Art is the guts of the people.”
—Elma Lewis (b. 1921)
“Your responsibility as a parent is not as great as you might imagine. You need not supply the world with the next conqueror of disease or a major movie star. If your child simply grows up to be someone who does not use the word “collectible” as a noun, you can consider yourself an unqualified success.”
—Fran Lebowitz (20th century)